Arts+Culture / NewsHigh doses of cocaine can cause the brain to ‘eat itself’According to new research, the drug can trigger ‘autophagy’ – a process that makes your cells actually digest themselvesShareLink copied ✔️January 19, 2016Arts+CultureNewsText Dominique Sisley We have partnered with The Global Drug Survey, the world’s largest of its kind, and the results of which are used to influence government drug policy. Last year, 100,000 people took the survey, with their invaluable insight into drug habits proving influential on a worldwide scale. Look out for editorial over the next month and tell us how you do drugs, who with, where and why. Take the survey here. Shocking new research has found that high doses of cocaine can cause your brain to “eat itself”. Experts from the Johns Hopkins University School of Medicine found that the drug can trigger an out-of-control reaction called “autophagy” – a process that makes your cells digest themselves. “A cell is like a household that is constantly generating trash,” revealed Dr Prasun Guha, the lead researcher of the project. “Autophagy is the housekeeper that takes out the trash – it’s usually a good thing. But cocaine makes the housekeeper throw away really important things, like mitochondria, which produce energy for the cell.” The study, which was published in the Proceedings of the National Academy of Sciences journal, was conducted on mice – with scientists pulling the results from post-mortems. They also found that authophagy-induced cell death could be passed on to children through pregnancy. Given that cocaine is the second most widely used illegal drug in the UK behind cannabis, this isn’t exactly great news for the nation. It also comes just months after another study revealed that a single dose of the drug can make empathy levels in users plummet. However, co-author Dr Maged Harraz insists that there are experimental remedies being worked on that may help reduce all that creepy self-cannibalising. According to the research, an experimental drug called CGP3466B was able to protect cells from cocaine death due to autophagy. “Cocaine works exclusively to modulate autophagy versus other cell death programs,” he added. “(So) there's a better chance that we can develop new targeted therapeutics to suppress its toxicity.” Escape the algorithm! Get The DropEmail address SIGN UP Get must-see stories direct to your inbox every weekday. Privacy policy Thank you. You have been subscribed Privacy policy Expand your creative community and connect with 30,000+ creatives from around the world.TrendingIn pictures: Wet hot summers at Berlin’s iconic inner-city pool Lucia Jost’s ongoing photo series, Prinzessinnenbad (The Princess Pool), documents the friendship groups who congregate at Berlin’s Sommerbad Kreuzberg poolArt & Photography Jordan Brand x Free The YouthFashionWhat went down at Jordan Brand x Free The Youth’s ‘Night of Flight’ Aveda BeautyAveda is kicking off healthy hair summerBeautyWhy are women now talking like looksmaxxers?FashionPure Sex: Photos from the relaunch of the cult 80s goth brandFashionPhotos of the ‘techno sluts’ at Berlin’s all-day runway raveBeauty10 of the hottest Instagram accounts fusing art, sex and eroticaMusicOn ‘Camera’: Unpacking Charli’s long love affair with filmArt & PhotographyThe Japanese photographers finding beauty in what others overlookEscape the algorithm! Get The DropEmail address SIGN UP Get must-see stories direct to your inbox every weekday. Privacy policy Thank you. You have been subscribed Privacy policy